iS Clinical for Hyperpigmentation, Ageing, Acne in London



"ACTIVE SERUM™ has simply transformed our treatment of acne and hyperpigmentation. The clinical results are exceptional. We love the predictable and reliable results. Our patients love their skin!"

Okiki Louis, MD, O Aesthetics, Smyrna, GA


"Science meets beauty! ACTIVE SERUM™ does more for your skin than 3 creams combined. It's great for clogged pores, mottled pigmentation and uneven texture. Dramatically improve the luster of your skin with this innovative mixture of scientifically proven ingredients."

Dr. Amy Lewis, Dermatologist, New York, NY


"The beauty of YOUTH COMPLEX® is its ingenius formulation that allows you to get amazing instant improvement of wrinkled skin while accomplishing significant long term improvements that patients clearly see. Solid science with solid results in an easy step application."

William L. Heimer II. MD


   iS Clinical is an established US cosmeceutical skin care brand dedicated to developing effective products that restore optimum skin health for people suffering from a variety of skin complaints. Formulated using only the highest pharmaceutical grade botanical ingredients, iS CLINICAL® is a globally acclaimed range of clinically proven luxury prescriptive cosmeceuticals. Developed by a leading anti-aging clinical team the brand prides itself on its global approach to R&D, which enables the unique ability to combine traditional botanical medicine with advanced technological formulation expertise.

The iS Clinical range features clinically proven and highly effective formulations and home care systems for treating medical skincare conditions such as Acne, Hyperpigmentation, Scar management and Rosacea as well as offering exceptional results within the anti-ageing market.


Acne (acne vulgaris) is a skin disease evidenced by clogged pores (blackheads and whiteheads), pimples, and larger cysts or nodules occurring mainly on the face, neck, chest, back, shoulders and upper arm area. Many factors, including genetics, stress, hormones, environment, heavy and/or oily makeup, and diet, all play roles. Acne is caused by dysfunction of the hair follicle and its accompanying sebaceous gland. The sebaceous gland produces sebum (the skins natural moisturizer), Acne begins to develop when keratin (found in hair, nails and the outermost layer of skin) over-accumulates and blocks the hair follicle (hyperkeratinisation) obstructing the flow of sebum.

iS CLINICAL products for acne are formulated with pharmaceutical-grade botanical ingredients that work synergistically and safely to clear the complexion. The Acne regime includes products that encourage exfoliation while addressing inflammation and infection.


Hyperpigmentation is a common condition in which darkening of the skin occurs due to an increase in melanin production. This darkening occurs when melanocytes (pigment-producing cells) over-produce melanin, forming concentrated deposits of brown pigment in the skin. Hyperpigmentation may be caused by sun damage, inflammation, hormonal changes, or skin injuries (including acne). Hyperpigmentation can occur anywhere on the body and affect all races.

iS CLINICAL ® products for hyperpigmentation are formulated with pharmaceutical-grade botanical ingredients that work synergistically and safely with skin cells to gradually lighten and even the appearance of pigmentation. The Hyperpigmentation Regime includes products that address overproduction of melanin, encourage exfoliation, and provide sun protection. Broad-spectrum UV sun protection is of paramount importance to treat this condition and prevent its reoccurrence.

Ageing skin

Research indicates that there are two types of aging that can affect your skin: intrinsic (internal), which is primarily genetic, and extrinsic (external), which is caused by environmental factors such as sun exposure and smoking. Both intrinsic and extrinsic aging are directly caused by oxidative stress (or free radical damage), a process by which destructive free radicals attack cells. Intrinsic aging is the “natural” and continuous aging process that begins in our mid-20s. Cellular turnover decreases and skin elasticity diminishes with the natural slowing of collagen and elastin production.

Extrinsic aging is an acceleration of the normal aging process, causing the skin to age prematurely. The main extrinsic cause of prematurely aging skin is due to sun exposure. Other factors include smoking, gravity, and repetitive facial expressions.


iS CLINICAL ® anti-aging products are formulated with pharmaceutical-grade botanical ingredients, clinically proven to help diminish the signs of aging on multiple levels. The Anti-Aging Regime includes products that provide antioxidant protection, reduce the appearance of wrinkling and hyperpigmentation, soothe symptoms of acne, and improve skin health.